跳至主要内容
临床试验/NCT04311827
NCT04311827已完成不适用

The Effect of the Serratus Anterior Plane Block in Improving Pain and Respiratory Function in Trauma Patients Presenting to the Emergency Department With Multiple Rib Fractures.

Stanford University1 个研究点 分布在 1 个国家目标入组 39 人开始时间: 2020年3月3日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
39
试验地点
1
主要终点
Change in pain score

研究概览

简要总结

This is an observational study which will evaluate the efficacy of the serratus anterior plane block for treating pain and respiratory capacity in patients with multiple rib fractures. When resources are available for a SAPB to be performed, patients will receive this block in addition to traditional pain medications, while at other times, patients will receive traditional pain medications only.

详细描述

Pain management by systemic analgesics and by nerve blocks are both standard of care and used in Emergency Department (ED) depending on the resources available. Not all ED physicians are trained or comfortable with the serratus anterior nerve block and thus it is not always available to patients and is provider dependent.

This is an observational study where patients with multiple rib fractures will receive either a serratus anterior plane block (SAPB) in addition to traditional forms of pain control when providers trained to perform the block are available, or will receive traditional forms pain control if trained personnel are not available. In addition to the serratus anterior plane block, standard forms of pain control in the Stanford Emergency Department include: oral or parenteral acetaminophen, oral or parenteral NSAIDs, oral or parenteral opiates, parenteral lidocaine, and parenteral ketamine.

Retrospective evaluation of the allocation of patients to either nerve block or no nerve block will be dictated by physician ability, time and resources to do the block. The efficacy of the block will be evaluated by serial measurements of pain score and respiratory capacity.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age greater or equal to 18 years of age
  • Presentation to Stanford University Hospital Emergency Department within 12 hours of a traumatic incident
  • Three or more anterior and/or lateral unilateral rib fractures diagnosed by CT
  • GCS 15, with the ability to discern and describe pain from rib fractures and give consent
  • Presentation to the Emergency Department between 7am and 11pm (for identification by research assistants)

排除标准

  • Posterior rib fractures
  • Bilateral rib fractures
  • Sternal fracture
  • Known allergy to local anesthetics
  • Significant coagulopathy
  • Hemodynamic instability

结局指标

主要结局

Change in pain score

时间窗: Before and 3 hours after analgesia administration

Patient reported pain score from 0-10 (0 - no pain, 10 = worst pain imaginable).

Change in incentive spirometry volume

时间窗: Before and 3 hours after analgesia administration

Maximum inspiratory respiratory volume (measured in ml) recorded on single use of incentive spirometer device

次要结局

  • Analgesia administration(Up to 3 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Youyou Duanmu

Clinical Assistant Professor

Stanford University

研究点 (1)

Loading locations...

相似试验