Satiety Study of a Carbohydrate Meal to a Highly Viscous Gel Meal

Phase 1

Completed

• Conditions: Obesity
• Interventions: Dietary Supplement: Konjac noodles; Dietary Supplement: Carbohydrate and Konjac Noodles; Dietary Supplement: Carbohydrate noodles

• Registration Number: NCT01875627
• Lead Sponsor: Unity Health Toronto

Brief Summary

To evaluate the effects of Konjac on satiety and subsequent food intake in healthy individuals.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-11
• Primary Completion: 2012-01
• Study Completion: 2012-01
• Study First Submitted: 2013-02-15
• Status Verified: 2013-05
• Study First Submitted QC: 2013-06-09
• Last Update Submitted: 2013-06-09
• Study First Posted: 2013-06-12
• Last Update Posted: 2013-06-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• Men and women
• Age 18-65 years
• Having a BMI of 18.5 - 25 kg/m2
• No presence of major disease

Exclusion Criteria

• Known history of liver or kidney disease, diabetes, hypertension, stroke or myocardial infarctions, thyroid disease, gastrointestinal disease, AIDS or AIDS-related complications; subjects using prescription medications or Natural Health Products; Subjects will be excluded if they have any condition which, in the opinion of the investigator, might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Carbohydrate Noodles	Konjac noodles	0g Konjac Noodles
Carbohydrate Noodles	Carbohydrate and Konjac Noodles	0g Konjac Noodles
Carbohydrate Noodles	Carbohydrate noodles	0g Konjac Noodles
Carbohydrate and Konjac Noodles	Konjac noodles	Half Carbohydrate and Half Non-Caloric Konjac Noodles - 122.5g Konjac
Carbohydrate and Konjac Noodles	Carbohydrate and Konjac Noodles	Half Carbohydrate and Half Non-Caloric Konjac Noodles - 122.5g Konjac
Carbohydrate and Konjac Noodles	Carbohydrate noodles	Half Carbohydrate and Half Non-Caloric Konjac Noodles - 122.5g Konjac
Konjac Noodles	Konjac noodles	Non-Caloric Konjac Noodles (viscous gel meal) - 240g Konjac
Konjac Noodles	Carbohydrate and Konjac Noodles	Non-Caloric Konjac Noodles (viscous gel meal) - 240g Konjac
Konjac Noodles	Carbohydrate noodles	Non-Caloric Konjac Noodles (viscous gel meal) - 240g Konjac

Primary Outcome Measures

Name	Time	Method
Objective Satiety	90 minutes	Objective satiety will be measured through subsequent food intake.; At each visit, participants will consume a pre-weighed snack (wafer cookies) that will be administered ad libitum at 90mins after consumption of the test meal. Subsequent food intake will be calculated by weighing the amount of the snack food left after consumption.

Secondary Outcome Measures

Name	Time	Method
Subjective Satiety	90 minutes	At each visit, participants will record their subjective satiety ratings using a 100 mm visual analogue scale and these rating will be combined into a total subjective appetite score using the formula (Q1+Q2+(100-Q3)+Q4)/4.

Trial Locations

Locations (1)

Risk Factor Modification Centre; 🇨🇦 Toronto, Ontario, Canada