Evaluation of Transcutaneous Posterior Tibial Nerve Electro Stimulation With or Without Low Dose Trospium Chloride in the Management of Overactive Bladder in Females
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Overactive Bladder
- Sponsor
- Alexandria University
- Enrollment
- 30
- Primary Endpoint
- Patient satisfaction
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
This study was done to verify whether the combination of transcutaneous posterior tibial nerve stimulation (TPTNS) with low dose trospium chloride in the treatment of females with overactive bladder (OAB) would be more effective than TPTNS alone after failure of behavioral therapy.
Detailed Description
The investigators randomized 30 women with OAB, in two groups: G I (15 patients) received 30 minutes TPTNS, three times a week; GII (15 patients) received TPTNS plus Low dose trospium chloride (20 mg once daily); all for 8 weeks. Patients were evaluated using Overactive Bladder Symptom Score questionnaire (OABSS), Incontinence Impact Questionnaire-short form 7 (IIQ-7), 3 day voiding diary and urodynamics at weeks 0 and 8.
Investigators
Amr Gaber Abdulfattah Ali Abulseoud
Urology Specialist
Alexandria University
Eligibility Criteria
Inclusion Criteria
- •Thirty adult female patients having OAB symptoms (wet type) and proved to have detrusor overactivity by urodynamics
Exclusion Criteria
- •Patients having urinary tract infection or bladder outlet obstruction.
- •Patients having neurological diseases.
- •Patients having gynecological problems as genital infection, pelvic organ prolapse or genital tumors.
- •Patients with electronic implants such as heart pacemakers.
- •During pregnancy
- •Patients subject to seizures
Outcomes
Primary Outcomes
Patient satisfaction
Time Frame: 1 year
Improvement in the questionnaire scores and associated willingness of the patient to continue treatment