Analysis of Outcomes and Adverse Events of Patients Undergoing Radiation Therapy. Quality Control Using Data Base of Patient Records 2000-2025
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 25,000
- 试验地点
- 1
- 主要终点
- Analysis of risk factors influencing outcome after radiation therapy
研究概览
简要总结
Analysis of outcomes and adverse events of patients undergoing radiation therapy. Quality control using data base of patient records 2000-2025
详细描述
What are the findings of the systematic recording and analysis of the outcomes and adverse events of radiotherapy, and how do these findings improve radiotherapy for future patients?
The goals of the systematic collection and analysis of patient-related personal data include:
- Quality assurance and showing where the quality can be improved
- Recording the outcomes and side effect profile of radiotherapy and adapting to prevent serious side effects in the future
- Presentation and publication as part of the clinical research program at the Institute for Radio-Oncology of the Winterthur Cantonal Hospital
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 105 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who are being treated with radiotherapy at the Department of Radiation Oncology at the Winterthur Cantonal Hospital
排除标准
- •No radiotherapy at the Department of Radiation Oncology at the Winterthur Cantonal Hospital <16 years,> 105 years
结局指标
主要结局
Analysis of risk factors influencing outcome after radiation therapy
时间窗: 25 years
Calculation of log-rank tests. If possible, hazard ratios are calculated via Cox regression. Competing risk analysis is conducted as supportive analysis
Overall survival (OS) and progression free survival (PFS) analysis after radiation therapy
时间窗: 25 years
Calculation of Overall survival (OS) and progression free survival (PFS). Time-to-event endpoints are summarized as the median and corresponding 95% confidence interval using Kaplan-Meier method
次要结局
- Number of patients with acute and late adverse events after radiation therapy(25 years)
研究者
Daniel Zwahlen
Head of Department of Radiation Oncology
Kantonsspital Winterthur KSW