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Clinical Trials/ISRCTN17573492
ISRCTN17573492
Completed
未知

A double-blind randomised placebo-controlled feasibility study to assess the impact of octreotide infusion during liver transplantation on post-operative renal failure.

niversity College London0 sites30 target enrollmentOctober 5, 2021
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ConditionsPerioperative bleeding, liver transplantSurgery

Overview

Phase
未知
Intervention
Not specified
Conditions
Perioperative bleeding, liver transplant
Sponsor
niversity College London
Enrollment
30
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
October 5, 2021
End Date
October 31, 2023
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity College London

Eligibility Criteria

Inclusion Criteria

  • •1\. Aged \=18 years
  • •2\. Undergoing primary liver transplantation of a whole or partial liver graft from a cardiac or brain dead donor
  • •3\. Provision of written informed consent

Exclusion Criteria

  • •1\. Previous solid organ transplant
  • •2\. Acute liver failure
  • •3\. Fulminant hepatic failure
  • •4\. Patients receiving a living donor liver graft
  • •5\. Patients currently admitted to ICU prior to transplantation
  • •6\. Requirement of haemodialysis or Continuous Veno\-Venous Hemofiltration (CVVHF) pre\-operatively
  • •7\. Known allergy or adverse reaction to octreotide
  • •8\. Pre\-operative decision to use intra\-operative CVVHF
  • •9\. A positive pregnancy test

Outcomes

Primary Outcomes

Not specified

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