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Clinical Trials/ACTRN12612000493842
ACTRN12612000493842
Completed
未知

An observational study of Alzheimer's disease, cognition and cerebrospinal fluid: Are they associated?

St. Vincent's Hospital0 sites54 target enrollmentMay 7, 2012
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ConditionsAlzheimer's DiseaseEffect of anaesthesia and surgery on cognitionCerebrospinal fluid (CSF) predictors of cognitive change and Alzheimer's diseaeAnaesthesiology - AnaestheticsNeurological - Alzheimer's diseaseMental Health - Studies of normal psychology, cognitive function and behaviour

Overview

Phase
未知
Intervention
Not specified
Conditions
Alzheimer's Disease
Sponsor
St. Vincent's Hospital
Enrollment
54
Status
Completed
Last Updated
6 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
May 7, 2012
End Date
April 4, 2016
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
St. Vincent's Hospital

Eligibility Criteria

Inclusion Criteria

  • •Patients aged 60y or more who are scheduled for elective total hip joint replacement (THJR) or total knee joint replacement (TKJR) who do not have neurological deficit; give informed consent; have no contraindication to neuropsychological testing; and reside in accessible proximity to the hospital to enable investigators to administer neuropsychological testing at patients' home.

Exclusion Criteria

  • •Pre\-existing neurological or clinically evident neurovascular disease (eg. stroke); Clnical Dementia Rating score \>\=1 (exclude frank dementia); anticipated difficulty with neuropsychological assessment, such as English not being the prime language, blindness, deafness; associated medical problems that may lead to significant loss to follow\-up (ASA physical status IV or higher); geographical remoteness.

Outcomes

Primary Outcomes

Not specified

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