Prevalence of dumping after bariatric surgery

Completed

Conditions: 10018424
hyperinsulinemic hypoglycaemia
late dumping
nesidioblastosis

Registration Number: NL-OMON36872

Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 60

Inclusion Criteria

Patients who underwent bariatric surgery between 2008 and 2011
Patients who participated and filled out a questionnary in earlier research
Informed Consent

Exclusion Criteria

Patients with diabetes mellitus
No Informed consent

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Prevalence of hyperinsulinemic hypoglycemia after gastric bypass<br /><br><br /><br>A serum glucose below 3,3 mmol/L combined with complaints of hypoglydcemia is<br /><br>defined as symptomatic late dumping.<br /><br>A serum glucose below 3,3 mmol/L without complaints is defined as asymptomatic<br /><br>late dumping.<br /><br>A serum glucose above 3,3 mmol/L is defined a no late dumping.<br /><br><br /><br>An increase in pulse-rate > 10 beats/minute or an increase in hematocrit > 3%<br /><br>before MMTT untill 30 minutes after a meal with complaints of dumping is<br /><br>defined as symptomatic early dumping.<br /><br>An increase in pulse-rate > 10 beats/minute or an increase in hematocrit > 3%<br /><br>before MMTT untill 30 minutes after a meal without complaints of dumping is<br /><br>defined as asymptomatic early dumping.<br /><br>Changes in pulse-rate < 10 beats/minute or a change in hemotocrittocriet < 3%<br /><br>is defined as no early dumping. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Sensitivity and specificity of the modified Sigstad score for early and late<br /><br>dumping.<br /><br>Descriptive research to the value of Coninuous Glucose Monitoring System in<br /><br>the Mixed Meal Tolerance Test.<br /><br>Determination of the extensiveness a the MMTT can be reduced in a more<br /><br>practical test for diagnosing dumping</p><br>