Evaluation of Effectivity of Bispectral Index Monitoring in Cases of Endoscopic Retrograde Cholangiopancreatography Received Sedoanalgesia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Sedoanalgesia
- Sponsor
- Istanbul Medeniyet University
- Enrollment
- 60
- Primary Endpoint
- Total dosage of propofol
- Last Updated
- 9 years ago
Overview
Brief Summary
The bispectral index (BIS) monitoring is an EEG-based method that uses electroencephalogram analysis and a complex algorithm to generate a numerical scoring 0-100 (0 flat line EEG, 100, wide awake) BIS monitoring allows noninvasive, objective measurement of level of consciousness of a sedated patient. A limited number of studies have used measurements of BIS monitoring to assist endoscopic sedation.There are studies using BIS monitoring to make sedation easy for ERCP procedures. However, the studies evaluating use of BIS for gastrointestinal endoscopy show inconsistent results.
The objective of this study is to evaluate effects of sedation on the dosage of propofol by monitoring with BIS values, hemodynamics, recovery parameters, respiratory functions and endoscopist satisfaction based on the hypothesis that the investigators would reduce the risk for respiratory depression using minimal doses of propofol in order to achieve the desired level of sedation with BIS monitoring.
Investigators
Ferda Yilmaz Inal
Assistant Professor
Istanbul Medeniyet University
Eligibility Criteria
Inclusion Criteria
- •20-75 years old
Exclusion Criteria
- •Emergency Operation
- •Those who had symptoms of neurological disease (TİA, syncope, dementia, etc.)
- •Patients that are allergic to drugs considered to use
Outcomes
Primary Outcomes
Total dosage of propofol
Time Frame: 1-3 hours
initial dose 1 mg.kg-1 of propofol, maintenance dose: infusion of 4 mg/kg/h . In case of insufficient sedation, additional dose of 0.1 mg/kg propofol (IV) by monitoring with BIS values 65-75 during procedure
The heart rate (HR)(n/dk)
Time Frame: 1-3 hours
During procedure
peripheral oxygen saturation (%)
Time Frame: 1-3 hours
During procedure
mean systolic-diastolic blood pressure(mmHg)
Time Frame: 1-3 hours
during procedure