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临床试验/NCT01671306
NCT01671306已完成不适用

The Association Between Monocyte Subsets and Coronary Collateral Development in Diabetes Mellitus

Samsun Education and Research Hospital0 个研究点目标入组 83 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
83

研究概览

简要总结

Monocyte heterogeneity in peripheral blood seems to be important in coronary collateral development in non-diabetic patients with stable coronary artery disease. Our aim in this study is to find out any possible relationship between the levels of circulating monocyte subsets and coronary collateral development in type 2 diabetic patients.

详细描述

83 diabetic patients with severe coronary artery disease were enrolled in the study. These patients were investigated according to their collateral development. Monocytes and their subtypes, namely CD14++CD16- and CD14+CD16+ cells were compared in 2 groups

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • presence of > 95% stenosis of at least one major coronary artery in their first coronary angiogram.

排除标准

  • Patients experiencing acute coronary syndrome either with or without ST elevation in the last one month
  • Evidence of ongoing infection and inflammation, known malignancy and chronic kidney disease

研究者

发起方
Samsun Education and Research Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ugur ARSLAN

Specialist of Cardiology

Samsun Education and Research Hospital

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