NCT07640321CompletedNot Applicable
Assessment and Comparison on 3 Groups of 25 Human Beings of the Effect on the Cutaneous State, the Dermis Echogenicity, the Moisturizing Effect, the Depigmenting Effect, the Effect on the Biomechanical Properties and the Effect on Wrinkles, Color and Homogeneity and Pigmentary Spots of Cosmetic Product N°1 vs Cosmetic Product N°2 vs Placebo After Oral Intake in Conditions of Normal Use During 28, 56 and 84 Days: Self-assessment of the Cosmetic Qualities and Efficacy
Wuhan CASOV Green Biotech Co., Ltd1 site in 1 country83 target enrollmentStarted: September 25, 2023Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 83
- Locations
- 1
Study Overview
Brief Summary
Evaluate and compare the effects on female facial skin of oral placebo (Product A), N-acetylneuraminic acid (Product B), and ACAI-PLUS (Product C) after 28, 56, and 84 days under normal usage conditions.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Cross Sectional
Eligibility Criteria
- Ages
- 40 Years to 65 Years (Adult, Older Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Skin type origin: Asian in China
- •Age: from 40 to 65 years old
- •Gender: female
- •Specific criteria:
- •All skin type on the face Dry, dry combination, normal
- •presenting with a lack of elasticity to the face, inclusion grade
- •≤ 6 according 10 points scale
- •presenting with a lack of density to the face, inclusion grade ≤ 6 according 10 points scale
- •presenting with wrinkles on crow's feet area, grade ≥ 2 according to Skin ageing atlas Vol.2 (p.41)
- •presenting with pigmentary spots with at least one with diameter ≥ 3mm
- •Usual or occasional user of food supplements
- •Able to give her informed consent
Exclusion Criteria
- •The non-inclusion general criteria were the following ones:
- •allergies or reactivity to cosmetic products,
- •for the subjects undergoing hormonal treatment; change of treatment within 3 months preceding the inclusion visit,
- •expectation of change in the current hormonal treatment during the study,
- •anti-allergic, antibiotic, anti-inflammatory, dermatological treatment or corticosteroid therapy within 2 weeks before the inclusion visit,
- •having a chronic pathology,
- •performing or prevision to perform another test during the study or during the exclusion period,
- •employee of the COSderma laboratory,
- •pregnant or breast-feeding woman,
- •woman not taking precaution to prevent pregnancy.
- •The non-inclusion specific criteria were the following ones:
- •application of care products to the face within 48 hours preceding the inclusion visit,
- •application of make-up products to the face the day of the inclusion visit,
- •face wash with any other means than clear water (no soap or cleanser) on the day of the inclusion visit,
- •application of self-tanning products to the face within 4 weeks preceding the inclusion visit,
- •Oral intake of food supplement within 1 month preceding the inclusion visit,
- •cutaneous marks on the face which could interfere with the skin's clinical signs assessment (pigmentation issues, scar tissues, over-developed hairiness, too many ephelides and naevi, sunburns...),
- •solar exposition (natural sun or UVA or heliotherapy treatment) within 4 weeks preceding the inclusion visit and expectation of solar exposition (natural or UVA) during the study,
- •Vitamin A acid treatment or its derivatives within 3 months preceding the pre-inclusion visit,
- •Retinoid based oral treatment within 6 months before the pre-inclusion visit, or local treatment within 2 months prior to this visit,
- •Carotene based treatment within 4 weeks preceding the inclusion visit,
- •expectation or having undergone aesthetic or dermatological surgery on the face.
Investigators
Study Sites (1)
Loading locations...
Similar Trials
Not yet recruiting
Not Applicable
Clinical Trial To Evaluate The Efficacy Of Siddharthakadi Lepa And Yavadi Lepa In YauvanpidikaCTRI/2026/04/108859Shiva Trust Yashwantrao Chavhan Ayurvedic Medical College and Hospital62
Not yet recruiting
Phase 2
A clinical study to see the result of Arjuna,Manjistha and Vasa patra churna lepa with Madhu Facial HyperpigmentationCTRI/2025/10/096162State Ayurvedic College and Hospital,Lucknow60
Completed
Phase 4
To Assess the Skin Tone Benefits of the Pearl Tomato® in Healthy AdultsCTRI/2024/08/072010Vesta Nutra40
Not yet recruiting
Not Applicable
To study the effect of a Sunscreen tablet in humans with pigmentation.CTRI/2025/10/095866Ajanta Pharma Limited36
Recruiting
Phase 3
To Assess the efficacy of Laghumanjisthadi Kashaya and Mahatrinaka Taila in Eczema ManagementCTRI/2024/07/069830National Institute of Ayurveda, Deemed to be university, Jaipur60