Everolimus- Versus Biolimus-Eluting Stents in All-Comers
- Conditions
- Coronary Artery Disease
- Registration Number
- NCT01472705
- Lead Sponsor
- University of Freiburg
- Brief Summary
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
- Detailed Description
A group of 814 consecutive patients undergoing percutaneous coronary intervention (PCI) was enrolled between 2007 and 2010, of which 527 were treated with EES and 287 with BES implantation. Clinical outcome was compared in 200 pairs using propensity score matching. The primary endpoint was a composite of death, myocardial infarction (MI) and target vessel revascularisation (TVR) at two-year follow-up.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 814
- all patients with at least one BES or EES for de novo stenosis
- patients with at least one non-study stent
- patients with both study stent
- patients with life expectancy < 3 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Composite of Death, Myocardial Infarction and Target Vessel Revascularization up to 24 months The primary outcome is the above mentioned composite of adverse events in order to measure their cumulative incidence (i.e. the rate of occurrence of such events in the study population over a predefined time periode).
- Secondary Outcome Measures
Name Time Method Cardiovascular death up to 24 months Any Revascularization up to 24 months
Trial Locations
- Locations (1)
Cardiology, university Fribourg Medical Center
🇨ðŸ‡Fribourg, Switzerland