Long-Term Comparison of Everolimus-Eluting and Biolimus-Eluting Stents in All-Comer Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 814
- 试验地点
- 1
- 主要终点
- Composite of Death, Myocardial Infarction and Target Vessel Revascularization
研究概览
简要总结
This study sought to investigate safety and efficacy of biolimus-eluting stents (BES) with biodegradable polymer as compared with everolimus-eluting stents (EES) with durable polymer through 3 years of follow-up.
详细描述
A group of 814 consecutive patients undergoing percutaneous coronary intervention (PCI) was enrolled between 2007 and 2010, of which 527 were treated with EES and 287 with BES implantation. Clinical outcome was compared in 200 pairs using propensity score matching. The primary endpoint was a composite of death, myocardial infarction (MI) and target vessel revascularisation (TVR) at two-year follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients with at least one BES or EES for de novo stenosis
排除标准
- •patients with at least one non-study stent
- •patients with both study stent
- •patients with life expectancy < 3 years
结局指标
主要结局
Composite of Death, Myocardial Infarction and Target Vessel Revascularization
时间窗: up to 24 months
The primary outcome is the above mentioned composite of adverse events in order to measure their cumulative incidence (i.e. the rate of occurrence of such events in the study population over a predefined time periode).
次要结局
- Cardiovascular death(up to 24 months)
- Any Revascularization(up to 24 months)
研究者
Stéphane Cook, Prof
Principal Investigator
University of Freiburg