Comparing Eye Pressure Using Maximal Tolerated Local Therapy or Systemic Acetazolamide
- Conditions
- Control of Elevated Eye Pressure by Local and Systemic Therapy
- Interventions
- Registration Number
- NCT01274039
- Lead Sponsor
- University of Cologne
- Brief Summary
Local therapy for glaucoma is known to induce a conjunctival inflammation. Because of this, trabeculectomy is more likely to fail. The investigators exchange the local therapy by systemic therapy using acetazolamide and measure the eye pressure using local therapy and systemic therapy using acetazolamide. The investigators suspect an elevated eye pressure using acetazolamide compared to local therapy. In summary acetazolamide could be a better choice in reference to conjunctival inflammation, but a worse choice in reference to controlling eye pressure.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- Not specified
- Patients with uncontrolled intraocular eye pressure
- Patients with planed trabeculectomy in 3 to 4 weeks
- Patients not meeting the inclusion criteria
- Patients with known intolerance to acetazolamide
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patient with a trabeculectomy planed Acetazolamide for glaucoma patients to lower eye pressure -
- Primary Outcome Measures
Name Time Method Eye pressure Once at the beginning of the study and once 3 to 4 weeks later The eye pressure is measured at the beginning of the study, when the patient is using the maximal tolerated local therapy and 3 to 4 weeks later, when using systemic acetazolamide treatment.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Cologne
🇩🇪Cologne, Germany