NL-OMON49690撤回不适用
Beta-alanine supplementation in patients with COPD receiving non-linear periodized exercise (NLPE) training: randomized placebo-controlled trial. - BASE-TRAI
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 入组人数
- 154
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. COPD group B or D (high symptomatic)
- •2. Grade 2 or higher on the modified Medical Medical Research Council (mMRC)
- •3. Clinically stable on the basis of clinical picture by pulmonary physician,
- •i.e. no exacerbation and/or hospitalization within the previous 4 weeks
- •4. Age between 40-80 years
- •5. Attending the regular rehabilitation program in Dekkerswald or CIRO and
- •receiving NLPE.
- •6. No use of anabolic steroids during the inpatient pulmonary rehabilitation
- •program in Dekkerswald and CIRO.
排除标准
- •1. Instable cardiac disease.
- •2. Participants treated with Neuromuscular Eletrical Stimulation (NMES)
- •3. History of drugs/alcohol abuse
- •4. Vegetarianism
- •5. Inability to understand the Dutch language
- •6. Self-reported beta-alanine supplementation in the past 3 months (wash-out
- •period is set at 9 weeks).
- •7. Participation in pulmonary rehabilitation within the past 12 months.
- •8. Inability to perform the incremental shuttle walk test
- •If the patient agrees to undergo a muscle biopsy, the following exclusion
- •criterion will also apply:
- •9. Patients with bleeding disorders, a recent trauma of the muscle or an
- •infection in the region of the proposed biopsy will be excluded for the muscle
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