Hemodynamically Important PDA in Newborns Under 32 Weeks: Clinical and Echocardiographic Findings and Outcomes
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Patent Ductus Arteriosus After Premature Birth
- Sponsor
- Ankara University
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Diameter of PDA
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
To define the characteristics of hemodynamically significant PDA by echocardiography, to investigate the systemic effects of the ductus with cerebral and renal Doppler flow studies, and to determine the oxygen consumption in the cerebral tissue with NIRS in newborns below 32 weeks of age with PDA.
Investigators
Özlem Bayram
Principal Investigator
Ankara University
Eligibility Criteria
Inclusion Criteria
- •Born at less than 32 weeks newborns
Exclusion Criteria
- •Congenital heart disease
- •Syndromic and/or major congenital anomaly
Outcomes
Primary Outcomes
Diameter of PDA
Time Frame: 1 year
Measurement the diameter of ductus in mm/weight using echocardiography
Velocity of internal carotid arteries, middle carotid arteries, anterior cerebral arteries and renal arteries
Time Frame: 1 year
Measurement velocity of internal carotid arteries, middle carotid arteries, anterior cerebral arteries and renal arteries using doppler ultrasonography
Velosity of PDA
Time Frame: 1 year
Measurement the velosity of ductus using CW doppler on ecocardiyograpy
Left ventricule expansion
Time Frame: 1 year
Measurement left ventricule end diastolic and end systolic diameter, left atrium/aort ratio on ecocardiography