Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements

Not Applicable

Completed

• Conditions: Skeletal Muscle Growth
• Interventions: Dietary Supplement: Whey protein supplement; Dietary Supplement: Soy protein supplement

• Registration Number: NCT03868631
• Lead Sponsor: Point Loma Nazarene University

Brief Summary

Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis. The purpose of this study is to determine whether matching soy and whey protein supplements for leucine content instead of by total protein content would contribute to differences in strength increases and muscle growth in response to 12 wk of resistance training.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-08-15
• Primary Completion: 2017-04-30
• Study Completion: 2017-04-30
• Study First Submitted: 2019-02-25
• Study First Submitted QC: 2019-03-06
• Study First Posted: 2019-03-11
• Status Verified: 2020-02
• Results First Submitted: 2020-02-03
• Results First Submitted QC: 2020-02-25
• Last Update Submitted: 2020-02-25
• Results First Posted: 2020-02-27
• Last Update Posted: 2020-02-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 61

Inclusion Criteria

• non-smoking
• body mass index (BMI) 18.5-24.9
• recreationally active

Exclusion Criteria

• participated in structured weight training during the previous 12 month
• vegetarian or vegan
• presence of chronic disease
• pregnant, postpartum up to six months, lactating, or intention to become pregnant
• allergy to whey or soy
• changes in body weight more than 10 pounds in the past three months

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Whey protein group	Whey protein supplement	-
Soy protein group	Soy protein supplement	-

Primary Outcome Measures

Name	Time	Method
Leg Girth Changes	Post-12 week intervention	assessed using circumference measurements (cm)
Lean Body Mass Change	Post-12 week intervention	assessed using dual energy x-ray absorptiometry (DEXA) scan for changes in lean body mass (kg)
Muscle Tissue Thickness Change	Post-12 week intervention	assessed using changes in muscle thickness assessed by ultrasound (cm)

Secondary Outcome Measures

Name	Time	Method
Change in Peak Torque When Doing Leg Extensions	Post-12 week intervention	Assessed using an isokinetic dynamometer set at 60 degrees of motion per second (d/s)

Trial Locations

Locations (1)

Arizona State University; 🇺🇸 Phoenix, Arizona, United States