Improved Heart Rate Variability, Inflammation Markers and Endothelial Function After Transcatheter Aortic Valve Implantation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Change of laboratory value of endothelial inflammation markers
研究概览
简要总结
Severe aortic valve stenosis is known to affect heart haemodynamics, endothelial function and body inflammation markers. Our aim is to investigate the weather transcatheter aortic valve implantation in patients with severe aortic stenosis affects heart rate variability, inflammation markers and endothelial function.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- •stage V chronic kidney disease
- •active malignancies
结局指标
主要结局
Change of laboratory value of endothelial inflammation markers
时间窗: 3 to 6 months after TAVI
Laboratory determined numerical changes in endothelial inflammation markers
Change of flow-mediated filatation (FMD) of the brachial artery
时间窗: 3 to 6 months after TAVI
% flow-mediated dilatation
Change of heart rate variability
时间窗: 3 to 6 months after TAVI
Change of heart rate variability (HRV) estimated with digital high resolution ECG recording
次要结局
未报告次要终点
研究者
Luka Vitez
Luka Vitez, MD, cardiology resident
University Medical Centre Ljubljana