To study whether Nerve pain medicine, Gabapentin will reduce narcotic pain medicine requirement following heart surgery
- Conditions
- Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
- Registration Number
- CTRI/2023/08/056487
- Lead Sponsor
- Anita Josprakash
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Elective CABG
2. Same surgical and anaesthetic team
3. Beating Heart Surgeries
4. Age between 35 and 70 years
5. BMI less than 35kg/m2
6. Ejection Fraction greater than 30%
1. Patient refusal to participate in the study
2. Patients with history of allergic reaction to gabapentin
3. Pregnant females
4. Patients posted for emergency surgeries, history of previous sternotomy or patients undergoing re-exploration sternotomy
5. Patients with history of comorbid diseases like neurological, psychiatric disorder or Alcohol dependence.
6. Patients with history of taking gabapentin or pregabalin in the past 3 months and chronic analgesic use, including opioids, NSAIDs or paracetamol etc.
7. Renal insufficiency (Serum Creatinine greater than 1.8)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To measure the opioid requirement intraoperatively & postoperatively <br/ ><br>2. Pain scores at 0,1,3,6,12,24,36,48 & 72 hours after extubationTimepoint: 5 days
- Secondary Outcome Measures
Name Time Method 1) Postoperative Quality of Recovery. <br/ ><br>2) Postoperative Nausea & vomiting. <br/ ><br>3) Hyper-sedation. <br/ ><br>4) Prolongation of mechanical ventilation.Timepoint: 5 days