Short Term Effect of Smoking Cessation on Human Metabolism

Completed

• Conditions: Smoking Cessation; Metabolic Syndrome
• Interventions: Behavioral: Smoking cessation workshops

• Registration Number: NCT03446183
• Lead Sponsor: Hebrew University of Jerusalem

Brief Summary

Investigating the short term smoking cessation on metabolism, examining of participant of smoking cessation workshops and former participants' file survey for metabolic aspects

Detailed Description

Objective: To examine metabolic aspects occurring during the first 6-12 months following smoking cessation in participants of smoking cessation workshops.

Design: A two armed study: prospective and retrospective. Prospective: Weight, BMI, waist circumference and waist: hip ratio were measured before, during and 6 months post cessation program. Retrospective: Blood test data for Blood fasting glucose (BFG) and lipid profile from the year preceding the workshops and the year after them were analyzed from participants' files. Smoking status was verified by phone conversation.

Study Timeline

• Study Start: 2016-04-18
• Primary Completion: 2017-09-01
• Study Completion: 2017-09-01
• Status Verified: 2018-02
• Study First Submitted: 2018-02-15
• Study First Submitted QC: 2018-02-20
• Last Update Submitted: 2018-02-20
• Study First Posted: 2018-02-26
• Last Update Posted: 2018-02-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 308

Inclusion Criteria

• Volunteers who were recruited from the smoking cessation workshops of the Meuhedet HMO (Israeli Health Services) during 2016-2017.

Exclusion Criteria

• Candidates with benign tumors, bariatric surgeries, and endoscopic bariatric procedures before or during the study period were excluded

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Smoking cessation prospective	Smoking cessation workshops	Smoking cessation workshops
Smoking cessation retrospective	Smoking cessation workshops	File review of former workshop participants

Primary Outcome Measures

Name	Time	Method
Change in weight	6 months from baseline	Weight in meters
Change in BMI	6 months from baseline	BMI in kg/m2
Change in waist and hip circumference	6 months from baseline	Waist and hip curcumference in centimeters
Change in Blood fasting glucose according to patient files (unspecified time points up to a year before and a year after the workshops)	up to 2 years from baseline	BFG in mg/dl
Change in lipid profile according to patient files (unspecified time points up to a year before and a year after the workshops)	up to 2 years from baseline	Lipid particle measurements in mg/dl