MedPath

All-poly Versus Metal-backed

Not Applicable
Active, not recruiting
Conditions
Osteoarthritis
Interventions
Device: Triathlon PS Knee System with all-polyethylene tibial components
Device: Triathlon PS Knee System with metal-backed modular components
Registration Number
NCT04358601
Lead Sponsor
Region Skane
Brief Summary

The primary objective is the assessment of prosthetic migration results after two years of the Triathlon PS Knee System with all-polyethylene tibial components compared to the Triathlon PS Knee System with metal-backed modular components by means of Roentgen Stereophotogrammetry.

Detailed Description

The secondary objective will be the prediction of the long-term survival based on the two-year migration patterns combined with clinical factors and radiographic aspects. In order to identify other clinical parameters besides the fixation of the prosthesis components, clinical scores and radiographic aspects will be correlated with the RSA outcome.

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
60
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
All-polyethylene tibial componentsTriathlon PS Knee System with all-polyethylene tibial componentsTriathlon PS Knee System with all-polyethylene tibial components
Metal-backed modular componentsTriathlon PS Knee System with metal-backed modular componentsTriathlon PS Knee System with metal-backed modular components
Primary Outcome Measures
NameTimeMethod
Migration, measured by means of RSA2 years

Migration (MTPM in mm) of the prosthesis with respect to the host bone measured by means of roentgen stereophotogrammetric analysis (RSA)

Secondary Outcome Measures
NameTimeMethod
Investigation of clinical performance and patient outcome with the Knee Injury and Osteoarthritis Outcome Score (KOOS) patient questionnairepre-operative, 3 months, 1, 2, 5, 7 and 10 years

KOOS consists of 5 subscales: Pain, other symptoms, function in daily living , function in sport and recreation and knee related quality of life (QOL). The previous week is the time period considered when answering the questions. Standardized answer options are given (5 Likert boxes) and each question is assigned a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms).

Migration, measured by means of RSA10 years

Migration (MTPM in mm) of the prosthesis with respect to the host bone measured by means of roentgen stereophotogrammetric analysis (RSA)

Investigation of clinical performance and patient outcome with the Knee Society Score (KSS)pre-operative, 3 months, 1, 2, 5, 7 and 10 years

The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, range of motion (ROM) and joint stability, and one for functional parameters. Sub-scores range from a potential minimum score of 0 to a maximum score of 100 points. Although the specific scores are not distinguished as "excellent," "good," "fair," or "poor," a higher value represents a better outcome.

Investigation of clinical performance and patient outcome with the Forgotten Joint Score (FJS) patient questionnaire.pre-operative, 3 months, 1, 2, 5, 7 and 10 years

The FJS consists of 12 questions and focuses on the patients' awareness of their joint replacement during a range of day to day and recreational activities. The score has a range of 0-100.questionnaire

Investigation of clinical performance and patient outcome with EuroQuol-5 dimension (EQ-5D) patient questionnairepre-operative, 3 months, 1, 2, 5, 7 and 10 years

The EQ-5D health questionnaire provides a simple descriptive profile and a single index value for health status.

Investigation of patient outcome with radiographic analysispre-operative, 3 months, 1, 2, 5, 7 and 10 years

Plain radiographs will be obtained for assessment of fixation of the device.

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