Renal cystic disease in lithium treated patients assessment by MRI and renal ultrasound.

Completed

• Conditions: microcysts; small renal cysts; 10038430

• Registration Number: NL-OMON38734
• Lead Sponsor: VUmc

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Inclusioncriteria (patients)
- patients (m/f, age *18 years) with a bipolar disorder treated with lithium

Exclusion Criteria

- general contra-indications for participation in a trial:
- inability to give informed consent
- pregnancy
- unstable psychiatric condition ;- Inability to undergo MRI.
- standard contra-indications for MR ( in accordance with the hospital protocol), such as the
presence of metallic fragments, clips or devices including implantable pacemakers and
implantable cardioverter-defibrillators, extreme overweight, claustrophia

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The prevalence and a semi-quantitative measurement of the number and size of<br /><br>microcysts in lithium treated patients.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Relation between MRI and ultrasound results * presence of microcysts * and<br /><br>clinical parameters (duration of lithium therapy, plasma lithium concentration,<br /><br>baseline plasma creatinine, sodium and potassium concentration and baseline<br /><br>urinary osmolality)</p><br>