Targeting Functional Recovery in Mood Disorders

Not Applicable

• Conditions: Mood disorders; Major depressive disorder; Bipolar disorder; Mental Health - Depression; Mental Health - Other mental health disorders

• Registration Number: ACTRN12616001328460
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-09-23
• Study Completion: 2021-02-05
• Last Update Posted: 10 May 2021

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

1. 18 years or over
2. At point of discharge from Community Outpatient teams of Specialist Mental Health Services
3. Bipolar I, II or NOS or Major Depressive Disorder (can be in a current episode)
4 Subjective cognitive difficulties reported by the patient or judged by his/her referring clinician

Exclusion Criteria

IPSRT in the last 18 months
CR in the last 6 months
Primary diagnosis of severe substance use disorder
Diagnosis of schizophrenia or schizoaffective disorder
ECT in the last 6 months
History of severe brain injury (loss of consciousness > hour)
Engaged in other therapy concurrently
Diagnosis of neurodegenerative disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in a composite cognitive score between baseline and 12 months The composite score will be calculated by computing z scores for each variable (change Baseline-Follow-up/standard deviation of the change). Scores will be adjusted so that a positive score reflects better performance for each variable. The z score for each variable will be added and divided by the number of variables to create a composite z score for change. The composite score is comprised of the following variables Groton Maze Learning Task - total errors, Rey Auditory-Verbal Learning Task - total words recalled lists 1-5 Rey Auditory-Verbal Learning Task - words recalled delayed recall Letter Fluency - total words, Category Fluency - total words Category Fluency Switching - total words Digit Span - total forwards plus backwards Timed Chase Test - time. [12 months]