Imaging in Inflammatory Bowel Disease (IBD)- A 4 way comparison study

Not Applicable

• Conditions: Inflammatory Bowel Disease; Crohn's disease; Ulcerative Colitis; Oral and Gastrointestinal - Crohn's disease; Oral and Gastrointestinal - Inflammatory bowel disease

• Registration Number: ACTRN12620000606987
• Lead Sponsor: Concord Repatriation General Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-25
• Last Update Posted: 1 June 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

1.Age >/= 18 years
2.Established CD or UC
3.Written and informed consent to participate

Exclusion Criteria

1.Women who are pregnant or are actively trying to fall pregnant
2.Patients taking non-steroidal anti-inflammatory drugs (NSAIDs) more than once a week in the 4 weeks leading up to disease re-assessment (either at baseline or at week 52)
3.Patients who are unable to communicate with the investigators and comply with the study requirements.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Proportion of patients with active inflammation as determined by each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule)[week 52]

Secondary Outcome Measures

Name	Time	Method
Sensitivity of each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule) in detection of active inflammation[week 52];Specificity of each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule) in the detection of active inflammation.[52 weeks];Positive predictive value of each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule) in the detection of active inflammation.[52 weeks];Negative predictive value of each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule) in the detection of active inflammation.[52 weeks];Severity of inflammation detected by each diagnostic modality (MRI, USS, colonoscopy, Pillcam Crohn's capsule).[52 weeks]