Evaluation of Liquorice Nanogel Versus Diode Laser as an Adjunctive Treatment for Patients With Periodontitis Stage Ⅲ.
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 27
- 试验地点
- 1
- 主要终点
- Quantitative analysis using real time pcr
研究概览
简要总结
Evaluation of the effect of liquorice nanogel versus diode laser on periodontitis stage Ⅲ clinically and microbiologically by molecular analysis of porphyromonas gingivalis using real time PCR.
详细描述
Quantitative analysis technique using real time pcr (polymerase chain reaction) was done to detect presence of porphyromonas gingivalis. Pocket depth (PD), Plaque index (PI), gingival index (GI) and Clinical attachment level (CAL) were measured before work and after 3 months postoperatively.
Analysis was made from gingival crevicular fluid samples of the patients using gutta percha paper points.
研究设计
- 研究类型
- 干预性
- 分配方式
- 随机
- 干预模型
- 平行分组
- 主要目的
- 治疗
- 盲法
- 单盲 (研究者)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- Patient had Periodontitis stage III with pocket depth ≥ 6mm; indicated for periodontal surgery or CAL ≥ 5mm.
- Patient agreed to the surgical procedure and clinical trial.
- Age ranged between 18-50 years old.
排除标准
- 1: No previous drug was taken affecting bone metabolism. 2- Smoking. 3- Pregnant women and women with menopause. 4- Patients with psychological problems . 5- Patients with abnormal habits. 6- Patients with medical conditions as Diabetes or Hypertension.
研究组 & 干预措施
control group
no drug was added to control group
干预措施: Liquorice Nanogel (Drug)
control group
no drug was added to control group
干预措施: diode laser (Drug)
Diode laser
Epic X 0.9watt device was used
干预措施: Liquorice Nanogel (Drug)
Diode laser
Epic X 0.9watt device was used
干预措施: diode laser (Drug)
Liquorice Nanogel
10% Liquorice was prepared in nanogel concentrate
干预措施: Liquorice Nanogel (Drug)
Liquorice Nanogel
10% Liquorice was prepared in nanogel concentrate
干预措施: diode laser (Drug)
结局指标
主要结局
Quantitative analysis using real time pcr
时间窗: 3 months
次要结局
未报告次要终点
研究者
Alaa Yousri Mohamed
Master Candidate of Oral and Dental Medicine and Periodontology Al Azhar University for girls
研究点 (1)
标识符
- NCT 编号
- NCT07602738
- 其他研究编号
- P-ME-24-10
日期
- 首次提交
- (4个月前)
- 首次发布
- (4个月前)
- 主要完成日期
- (去年)
- 研究完成日期
- (6个月前)
- 最近核实
- (5个月前)
- 最近更新
- (昨天)
监管与共享
- FDA 监管药物
- 否
- FDA 监管器械
- 否
- 个体参与者数据共享计划
- UNDECIDED
- 是否有结果
- 否