Phase II study of pematrexed plus carboplatin in previously untreated non-small cell, non-squamous cell lung cancer
Phase 2
- Conditions
- nresectable non-small cell lung cancer with EGFR mutations (non-squamous histology)
- Registration Number
- JPRN-UMIN000002846
- Lead Sponsor
- Hokkaido Lung Cancer Study Group
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1) Active infection 2) fever >= 38C 3) Severe and uncontrolled complication 4) Other active malignancies 5) Unstable metastases to the brain 6) Uncontrolled pleural, pericardial effusion or ascites 7) Presence of active interstitial pneumonia 8) Allergy to treatment drugs 9) Pregnant patients 10) Unstable psychic disorder 11) Continuous use of steroid 12) Decision of ineligibility by a physician
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate
- Secondary Outcome Measures
Name Time Method safety, overall survival, and progression-free survival