RBR-9hpwgjy
Recruiting
未知
Brain Biomarkers as Response Predictors to Selective Serotonin Reuptake Inhibitors in Obsessive-Compulsive Disorder: development of a paradigm towards personalized medicine
Instituto de Psiquiatria0 sitesMarch 15, 2022
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Obsessive-Compulsive Disorder with predominance of obsessive ideas or ruminations
- Sponsor
- Instituto de Psiquiatria
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male or female aged between 18 and 50 years; Main diagnosis of Obsessive\-Compulsive Disorder according to DSM\-5; Y\-BOCS score \= 16; No psychotropic medication used in the last 6 weeks; No behavioral therapy or response prevention exposure focusing on Obsessive\-Compulsive Disorder in the past 6 weeks; Able to tolerate a 1\-week treatment\-free period; and Able to provide informed consent.
Exclusion Criteria
- •Lifetime diagnosis of psychotic disorder, bipolar disorder, anorexia nervosa, autistic spectrum disorder with IQ\<80, Tourette's disorder; Current chronic tic disorder (current \= within the last 12 months); Disorders related to the use of current substances, including nicotine (current \= within the last 12 months); Current eating disorder or bulimia (current \= within the last 12 months); Acute risk of suicide. Pregnant women; Medical or neurological problems (including head trauma with loss of consciousness); Presence of metal devices on the body or dental appliances; IQ\<80; Cigarette use: more than 5 per day; Alcohol use: more than 2 drinks a day for women
- •and more than 3 drinks a day for men; Cannabis use: more than once a week.
Outcomes
Primary Outcomes
Not specified
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