Clinical and histologic effect of transrectal intraprostatic injections with botulinum toxin A in patients with lower urinary tract symptoms caused by benign prostatic hyperplasia.
- Conditions
- Benign prostatic hyperplasia
- Registration Number
- NL-OMON20354
- Lead Sponsor
- niversity Medical Center Utrecht, Utrecht The Netherlands
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1. Age > 55
2. Signed informed consent
Exclusion Criteria
1. Neuropathic bladder dysfunction
2. Prostatic carcinoma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptom relief according to the International Prostatic Symptom Score(IPSS)
- Secondary Outcome Measures
Name Time Method 1. Urodynamic obstruction (according to Schafer) <br /><br>2. Post void residual <br /><br>3. Decrease in prostate volume <br /><br>4. Histologic change after 1 month<br /><br>5. PSA change <br /><br>6. Other treatment needed<br /><br>