NL-OMON46873
招募中
不适用
euronal correlates of post-stroke epilepsy and the associated cognitive impairment - PoSECI-7T
Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 72 人待定
概览
- 阶段
- 不适用
- 干预措施
- 未指定
- 疾病 / 适应症
- 未指定
- 发起方
- Medisch Universitair Ziekenhuis Maastricht
- 入组人数
- 72
- 状态
- 招募中
- 最后更新
- 2年前
概览
简要总结
暂无简介。
研究者
入排标准
入选标准
- •\- Patients suffering from stroke (and post\-stroke epilepsy), including both brain infarction, cerebral hemorrhage and clinically significant hemorrhagic transformation of stroke (or a primary intracerebral hemorrhage)
- •\- Patients suffering from post\-stroke epilepsy after cortical stroke defined as one or more unprovoked epileptic seizures occurring more than one week after the stroke, according to International League Against Epilepsy criteria.
- •\- Patients suffering from cortical stroke, with the onset of acute stroke symptoms more than 4 months prior to inclusion.
- •\- Age \> 18 years
排除标准
- •\-onset of stroke (and epilepsy for post\-stroke epilepsy patients) less than 4 months ago
- •\-In case of the PSE group: onset of epilepsy within a week or 2 years after the onset of stroke.
- •\-previous history of epilepsy
- •\-history of another cerebral disorder (neurodegenerative diseases, tumours)
- •\-inability to provide informed consent
- •\- any contraindication for MRI: metallic foreign body, pacemaker, claustrophobia, pregnancy, tattoos, permanent make\-up.
- •\- known contrast allergy to gadolinium, insufficient kidney function (eGFR\<\=30\).
- •\- A history of topiramate use as an anti\-epileptic drug, because of its known cognitive effects.
结局指标
主要结局
未指定
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