ow- and moderate-intensity Statin and Clinical Outcome of Primary prevention in individuals aged >75 years: the SCOPE-75 RCT Study

Yonsei University Health System, Severance Hospital0 个研究点目标入组 2,484 人开始时间: 待定最近更新: 2020年2月24日

试验速览

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•1) Individuals aged 76-85 years old.
•2) Individuals who have serum LDL-cholesterol of 160-189 mg/dL.
•3) Individuals who have serum LDL-cholseterol of 80-159 mg/dL and =1 cardiovascular risk factor (male, diabetes, hypertension, smoking, serum HDL-cholesterol <40 mg/dL, or family history of premature cardiovascular disease).

•1) Individuals who have been diagnosed with cancer within the last 5 years.
•2) Individuals who have high level of serum AST and ALT (>2 upper normal limit).
•3) Individuals who have muscular disease such as Myopathy or Rhabdomyolysis or who have high level of CK (>2 upper normal limit).
•4) Individuals who have serum creatinine =2 mg/dL.
•5) Individuals who have been diagnosed with cardiovascular disease (>50% stenosis of coronary artery on imaging study, percutaneous transluminal coronary angioplasty, coronary artery bypass graft, or myocardial infarction).
•6) Individuals who have been diagnosed with peripheral artery disease (>50% stenosis of peripheral artery on imaging study, or ankle brachial index <0.9 or =1.3).
•7) Individuals who have been diagnosed with uncontrolled hyperthyrodism or hypothyroidism.
•8) Individuals who are taking drug that can interact with statin.
•9) Individuals who have physical disability to live daily life.

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