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Clinical Trials/NCT04514276
NCT04514276
Active, not recruiting
Not Applicable

Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway for High-risk Pregnant Women Because of Fetal Growth Restriction

Technische Universität Dresden2 sites in 1 country828 target enrollmentJune 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pre-Eclampsia
Sponsor
Technische Universität Dresden
Enrollment
828
Locations
2
Primary Endpoint
Evaluation of patients' safety: newborn's birthweight adjusted by gestational age
Status
Active, not recruiting
Last Updated
3 years ago

Overview

Brief Summary

Due to the fetoneonatal pathway it is possible to identify pregnant women with an increased risk of fetal growth restriction or pre-eclampsia in early stages (from 10th week of pregnancy). Women whose pregnancy is considered high-risk receives risk-adapted prenatal treatment as well as certain treatments for their newborn and infant until 1 year of age. The tasks of all involved persons are defined by standard operating procedures (SOP)

Detailed Description

By implementing a preventive feto-neonatal pathway, healthcare for pregnant women with high risk of fetal growth restriction (FGR) or pre-eclampsia will be improved and, therefore the occurence of children's health problems may be prevented.The pathway allows healthcare to be structured, ross-sectoral, inter- and multidisciplinary in consideration of medical and psychosocial imensions. The feto-neonatal pathway transfers scientific findings, which already determine international routine care, in the project region into clinical routine care. The anamnestically increased risk for FGR or pre-eclampsia is validated by ultrasound and the identified high-risk pregnancy is attended risk-adapted from birth until the end of the first year of life of the child.As a result, the mothers' pregnancy-related risks (death, premature delivery, traumatic stress disorders) as well as risks for the child (prematurity and associated problems, childhood growth restriction with the risk of metabolic syndrome, developmental neurological problems) are reduced and the sustainability of the interventions is ensured in the long term through improved health competence of the families. The feto-neonatal pathway shows how highly specialised fetoneonatal care of high-risk pregnancies can be ensured while ensuring primary care in a health region, and offers the possibility of being extended to other indications.

Registry
clinicaltrials.gov
Start Date
June 1, 2020
End Date
March 31, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Female, minim. 10 weeks of pregnancy, maximum 36 weeks of pregnancy
  • anamnestic risk of preeclempsia or fetal growth restriction
  • being part of the project region

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Evaluation of patients' safety: newborn's birthweight adjusted by gestational age

Time Frame: through study completion, an average of 1 year and 7 months

self-designed questionnaire, health information

Evaluation of patients' safety: maternal morbidity

Time Frame: through study completion, an average of 1 year and 7 months

self-designed questionnaire, health information

Evaluation of patients' safety: infantil morbidity

Time Frame: through study completion, an average of 1 year and 7 months

self-designed questionnaire, health information

Evaluation of patients' safety: Quality of life

Time Frame: through study completion, an average of 1 year and 7 months

Questionnaire: Quality of Life (Angermayer, Kilin \& Matschinger, 2000)

Evaluation of patient's access to treatment and satisfaction

Time Frame: through study completion, an average of 1 year and 7 months

self-designed questionnaire

claim of the health services

Time Frame: From admission to discharge, study inclusion to one year postpartum)

based on self-designed questionnaires

Evaluation of patients' safety: maternal pre-eclampsia rate

Time Frame: through study completion, an average of 1 year and 7 months

self-designed questionnaire, health information

Evaluation of patients' safety: attachment behavior

Time Frame: through study completion, an average of 1 year and 7 months

Questionnaire: Postpartum Bonding Questionnaire (Reck et al., 2006)

duration of unemployability

Time Frame: From admission to discharge, study inclusion to one year postpartum)

based on self-designed questionnaires

prohibition of employment

Time Frame: From admission to discharge, study inclusion to one year postpartum)

based on self-designed questionnaires

Secondary Outcomes

  • evaluation of ungoing processes during the fetoneontal health care pathway: effectiveness of fetoneonatal health care(From admission to discharge, study inclusion to one year postpartum)
  • evaluation of ungoing processes during the fetoneontal health care pathway: the pathway's maintenance being long term part of routine health care(From admission to discharge, study inclusion to one year postpartum)
  • evaluation of ungoing processes during the fetoneontal health care pathway: target patients(From admission to discharge, study inclusion to one year postpartum)
  • health economical evaluation(From admission to discharge, study inclusion to one year postpartum)
  • evaluation of ungoing processes during the fetoneontal health care pathway: implementation of participating employees(From admission to discharge, study inclusion to one year postpartum)
  • evaluation of ungoing processes during the fetoneontal health care pathway: participation of health care provider(From admission to discharge, study inclusion to one year postpartum)

Study Sites (2)

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