ISRCTN56543987已完成不适用
Prevention by HMGCoA reductase inhibition of Acute Lung Injury (ALI) associated with one lung ventilation following oesophagectomy by a reduction of pulmonary vascular dysfunction and inflammatio
The Royal Group of Hospitals Trust (UK)0 个研究点目标入组 40 人开始时间: 2007年5月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Adult patients undergoing oesophagectomy.
排除标准
- •1. Age < 18 years
- •2. Pregnancy
- •3. Creatine Kinase (CK) > 5 times upper limit of normal range
- •4. Transaminases > 3 times upper limit of normal range
- •5. Severe renal impairment (calculated creatinine clearance less than 30 mL/minute)
- •6. Severe liver disease (Child?s Pugh score > 11)
- •7. Participation in other trials within 30 days
- •8. Current treatment with statins
- •9. Inability to take oral medication pre-operatively
- •10. Patients taking corticosteroids or non-steroidal anti-inflammatory drugs
- •11. Consent declined
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