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Clinical Trials/NCT06188143
NCT06188143
Completed
N/A

The Efficacy of Combination of Ibuprofen and Paracetamol for Pain Control in Diagnostic Hysteroscopy

Phramongkutklao College of Medicine and Hospital1 site in 1 country58 target enrollmentDecember 22, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Pain, Postoperative
Sponsor
Phramongkutklao College of Medicine and Hospital
Enrollment
58
Locations
1
Primary Endpoint
The pain score comparing between study and control group
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The goal of this clinical trial study is to learn about how to decrease the pain during the diagnostic hysteroscopy. The main question it aims to answer is "Do the Paracetamol and Ibuprofen taken before the procedure can lower the pain during the diagnostic hysteroscopy".

Detailed Description

After the participants those are indicated for diagnostic hysteroscopy and eligible for the study undergo informed consent, then they were divided to two groups for control group those get no medication and study group those get Paracetamol 500mg and Ibuprofen40mg per oral before the hysteroscopy, and both group needs to evaluate the pain score in VAS before, during hysteroscopy and after hysteroscopy for 30 minutes to compare the pain level in two groups.

Registry
clinicaltrials.gov
Start Date
December 22, 2022
End Date
June 22, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Phramongkutklao College of Medicine and Hospital
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Women with indication and informed to undergo diagnostic hysteroscopy over or equal the age of 20 years old

Exclusion Criteria

  • Women with contraindication for undergoing diagnostic hysteroscopy includes women with pregnancy, uterine infection, diagnosed with cervical cancer or endometrium cancer and women who is undergoing with active vaginal bleeding
  • Women with history of allergy to Paracetamol or Ibuprofen medicine
  • Women with currently or pre-existing medical conditions that contraindicate the use of ibuprofen includes kidney disease, heart disease, cirrhosis, gastritis or individuals with a history of peptic ulcer or gastrointestinal bleeding
  • Women with currently taking anticoagulant or antiplatelet medications
  • Women with history of psychiatric disorders

Outcomes

Primary Outcomes

The pain score comparing between study and control group

Time Frame: During and 30minutes after the hysteroscopic procedure

Comparing the pain score in visual analogue scale of 1(minimum) to 10scores(maximum) which is less to more painful respectively(higher score means more painful and worse outcome)

Secondary Outcomes

  • The associated factors effecting the pain of the procedure(During and 30minutes after the hysteroscopic procedure)

Study Sites (1)

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