The effects of botulinum toxin A on patients with idiopathic detrusor overactivity. A double-blind, randomised, placebo-controlled trial.

Completed

• Conditions: Overactive bladder symptoms and idiopathic detrusor overactivity.; Urological and Genital Diseases; Other disorders of bladder

• Registration Number: ISRCTN16995641
• Lead Sponsor: Guy's and St Thomas' NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-10-19
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

1. Refractory to traditional anticholinergic therapy either due to poor efficacy or side effects
2. Proven detrusor overactivity on urodynamic studies
3. Detrusor overactivity of non-neurogenic origin

Exclusion Criteria

1. Pregnancy or planned pregnancy
2. Breast Feeding
3. Indwelling catheter
4. Current anticoagulation e.g. heparin or warfarin
5. Neurogenic detrusor overactivity
6. Painful bladder syndromes
7. Previous bladder surgery e.g. augmentation cystoplasty

Study & Design

• Study Type: Interventional
• Study Design: Not specified