A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy
- Conditions
- Pneumoperitoneum
- Registration Number
- NCT02619656
- Lead Sponsor
- University of Utah
- Brief Summary
The investigators hypothesize that using carbon dioxide for PEG placement versus using room air will decrease post-procedure pneumoperitoneum as well as improve post-procedure bloating/pain, and waist circumference.
- Detailed Description
Background and study aims: Pneumoperitoneum following PEG placement has been reported in up to 60% of cases, and while usually benign and self-limited, it can lead to evaluation for suspected perforation. This study was designed to determine whether using CO2 compared to ambient air for insufflation during PEG reduces post-procedure pneumoperitoneum.
Patients and Methods: Prospective, double blind, randomized trial of 35 consecutive patients undergoing PEG at a single academic medical center. Patients were randomized to insufflation with CO2 or ambient air. Primary outcome was pneumoperitoneum determined by left-lateral decubitus abdominal x-rays 30 min after PEG placement. Secondary endpoints included abdominal distention, pain, and bloating.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 35
- Participants must be over the age of 18 and need a percutaneous endoscopic gastrostomy
- None
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Post-procedure pneumoperitoneum left-lateral decubitus abdominal x-rays 30 min after PEG placement. Frequency of post pneumoperitoneum determined by left-lateral decubitus abdominal x-rays 30 min after PEG placement.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Utah SOM
🇺🇸Salt Lake City, Utah, United States
University of Utah SOM🇺🇸Salt Lake City, Utah, United States