EUCTR2013-002709-79-NL进行中（未招募）不适用
Mechanism of action study of anti-IL17 treatment in spondyloarthritis: Impact on cellular and molecular pathways of synovial inflammation and tissue remodeling. - Mechanism of action of anti-IL17 in spondyloarthritis
Academic Medical Center, Department of Rheumatology0 个研究点开始时间: 2014年1月16日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-Male or non-pregnant/non-lactating females age 18-70
- •- Diagnosis of SpA according to ESSG criteria and/or ASAS criteria
- •- Active disease defined by =1 swollend and = 1 tender joint, and at least 1 swollen knee or ankle joint at baseline
- •- stable dose of concomitant medication (NSAIDs etc.)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 20
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •- Evidence for infectious or malignant process (on chest X ray/MRI etc)
- •- Pts taking opioid angalgetics
- •- Previous IL-17 therapy exposure
- •- Previous use of celldepleting therapies, biological immunomodulants (except for a.TNF)
- •- Significant medical problems or diseases
研究者
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