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Biomarkers for Angiogenesis in Renal Cell Carcinoma and Neuro-endocrine Tumours.

Completed
Conditions
clear cell renal cell carcinoma
kidney cancer
10038364
Registration Number
NL-OMON35791
Lead Sponsor
niversitair Medisch Centrum Groningen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
40
Inclusion Criteria

1. Age 18 years or older
2. Patients with clear cell renal cell carcinoma with metastases or patients with a low-grade neuro-endocrine tumor with metastases
3. Written informed consent

Exclusion Criteria

1. Use of L-dopa or SSRI
2. Patients with a second primary malignancy

Study & Design

Study Type
Observational invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Difference in concentrations DA and 5-HT in thrombocytes of patients with clear<br /><br>cell renal cell carcinoma and healthy controls, and patients with low grade<br /><br>neuroendocrine tumours and healthy controls.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Difference in concentrations DA and 5-HT in thrombocytes of patients with clear<br /><br>cell renal cell carcinoma and low grade neuroendocrine tumours before start of<br /><br>a treatment cycle and during a treatment cycle.</p><br>
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