Causality of Poisoning of the Elderly: Prospective Study Based on Data From the Poison Control Centre of Bordeaux

Completed

• Conditions: Intoxication

• Registration Number: NCT03726632
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

Elderly is often associated with social, physiological and psychic changes. However, no study has examined accidental poisoning-induced changes.

The objective of the study is to identify and analyze the various causes of potentially toxic accidental exposure of the elderly to determine preventable causes and propose prevention strategies.

Detailed Description

Elderly is often associated with social, physiological and psychic changes. Many studies tried to demonstrate their influence in the genesis of pathological events such as falls or suicide of the elderly but none on the genesis of accidental poisoning.

However, poisoning in this age group is frequent and sometimes severe. In order to improve care of the elderly, it seems necessary to focus on potential toxic accidental exposure.

For this, Poison Control Centre of the University Hospital of Bordeaux has identified the causes over a period of 5 months (from 01 March to 31 July 2017) from calls to the centre.

Study Timeline

• Study Start: 2017-04-03
• Primary Completion: 2017-08-02
• Study Completion: 2017-08-02
• Study First Submitted: 2018-10-12
• Study First Submitted QC: 2018-10-29
• Study First Posted: 2018-10-31
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-07
• Last Update Posted: 2025-02-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

• All subjects aged 65 and over,
• Victims of accidental exposure regardless of the agent (drug, household product, plant ...)
• Victims of voluntary exposure (out of suicidal behavior)
• And for which a call (notice, report) to the Poison Control Centre of Bordeaux has been recorded.
• Calling dates between March 1st and July 31st, even if the exhibition is prior to March 1st, 2017).

Exclusion Criteria

• Suicide
• Calls for inquiries

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nature of the agent	Baseline	The nature of the agent has to be chosen among (1 choice only): drug, chemical, household product, DIY product, phytosanitary product, gas, plant, foreign body, food

Secondary Outcome Measures

Name	Time	Method
Concomittant treatment	Baseline	Number of prescription drugs
Circumstance of the event	Baseline	The circumstance of the event has to be chosen among (1 choice only): accidental / voluntary
Exposition route of exposure	Baseline	The exposition route of exposure has to be chosen among (1 choice only): ingestion, eyepiece, dermal, inhalation or multiple routes
symptoms	Baseline	Number / Nature
Poisoning Severity	Baseline	The poisoning severity is evaluated using the Poisoning Severity Scale (PSS score). Severity grades: None (No symptoms or signs related to poisoning); MINOR (Mild, transient and spontaneously resolving symptoms); MODERATE (Pronounced or prolonged symptoms); SEVERE (Severe or life-threatening symptoms); DEATH
Death	Baseline	death before the call
packaging of the agent	Baseline	The packaging of the agent has to be chosen among (1 choice only): solid, liquid, gaseous, powder and if drug: tablet, drops, syrup, patch, injectable
Frailty status	Baseline	The frailty status is calculated from the following factors: sensory disturbance, cognitive and/or neurological disorder, psychiatric disorder, autonomy / dependence, concomittant treatments

Trial Locations

Locations (1)

Centre Anti Poision du CHU de Bordeaux; 🇫🇷 Bordeaux, France