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Comparison of intravenous remifentanil and intravenous lidocaine in prevention of cardiovascular response following laryngoscopy and tracheal intubation under genereal anesthesia in limbs surgery.

Phase 3
Conditions
Condition 1: Open reduction and internal fixation of ulna and radius fracture. Condition 2: Open reduction of humerus fracture. Condition 3: Open reduction of tibia fractures.
Fracture of shaft of radius
Fracture of lower end of humerus
Fracture of lower end of tibia
S52.4
S42.4
S82.3
Registration Number
IRCT20200501047255N1
Lead Sponsor
Shahroud University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
60
Inclusion Criteria

Open limbs surgery under general anesthesia
Class 1 and 2 of anesthesia risk (According to American society of anesthesiologist's classification),

Exclusion Criteria

Difficult intubation
prolonged ( more than 30 seconds) attempts at laryngoscopy
Repeated attempts at laryngoscopy

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Blood pressure. Timepoint: Before induction of anesthesia and just following laryngoscopy and tracheal intubation. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.;Pulse rate. Timepoint: Before induction of anesthesia and just following laryngoscopy and tracheal intubation. Method of measurement: Non-invasive blood pressure measurement with Novin Saadat monitor.
Secondary Outcome Measures
NameTimeMethod
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