EUCTR2005-001930-34-DK进行中（未招募）不适用
eft ventricular reverse remodelling after aortic valve replacement in severe valvular aortic stenosis - effect of blockade of the angiotensin-II receptor
Department of Cardiology, Odense University Hospital0 个研究点开始时间: 2005年11月25日最近更新:
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Inclusion criteria
- •1.Symptomatic severe AVS referred for valve replacement (mechanic prosthesis or bioprosthesis) at Odense University Hospital
- •2.Age > 18 years
- •3.Signed informed consent
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •Exclusion criteria
- •1.Severe renal failure (s-creatinine >300 mmole/l)
- •2.Moderate or severe hepatic failure (ALAT >150 IU/l)
- •3.Moderate or severe LV systolic dysfunction (LVEF<40%)
- •4.Known intolerance for angiotensin II receptor antagonist (Atacand)
- •5.Unwilling to participate in the study
- •6.Poor echocardiographic window
- •7. Women of childbearing potential (only postmenopausal women)
研究者
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