Frequency and Origin of Dysnatremias in the Emergency Department

Withdrawn

• Conditions: Hyponatremia; Hypernatremia

• Registration Number: NCT01326429
• Lead Sponsor: Insel Gruppe AG, University Hospital Bern

Brief Summary

Hypo- and hypernatremia are the most frequent electrolyte disorders found in hospitalized patients. The increasing use of diuretics and other medications influencing the water and sodium homeostasis potentially lead to a rise in the prevalence of the electrolyte disorders. Only little data is available on the frequency and the mechanisms leading to hypo-/hypernatremia.

Thus, the investigators aim to A.) determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital and B.) explore the mechanisms leading to the development of dysnatremias by detailed clinical and laboratory examinations.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2011-03-29
• Study First Submitted QC: 2011-03-29
• Study First Posted: 2011-03-30
• Study Start: 2011-10
• Primary Completion: 2013-03
• Study Completion: 2013-03
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-22
• Last Update Posted: 2015-07-23

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Serum sodium below 135 mmol/L (i.e. hyponatremia); serum sodium exceeding 145 mmol/L (hypernatremia)

Exclusion Criteria

• Patients below age 18 years; patients declining study participation.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of hypo- and hypernatremia in the emergency department	approx. 6 months	The investigators aim to determine the frequency of hypo- and hypernatremia in the emergency department of a large tertiary university hospital.

Secondary Outcome Measures

Name	Time	Method
Origin of hypo- and hypernatremia in the emergency department	approx. 6 months	The investigators try to investigate the mechanisms leading to the development of hypo- and hypernatremia in patients admitted to the emergency department.