Eye nerve diameter measurement with USG after prolonged abdominal surgery

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2021/03/031613
• Lead Sponsor: Department of Anaesthesia Critical Care and Pain

Brief Summary

•Prolonged abdominal surgery incurs large amount of blood loss, rapid fluid replacement and fluid shifts across physiological barriers causing tissue edema and raised ICP.

•Added conditions such as- pneumoperitonium, trendelenberg position increase ICP further.

•Raised ICP is reflected in Optic nerve sheath diameter (ONSD) as the ON is surrounded by dural sheath and increased CSF pressure causes the sheath to swell.

ONSD measured at 3 mm below the optic disc using a high frequency linear ultrasound transducer (UST) is

•Safe, reliable, >90% accuracy

•Can be performed by any anaesthesiologist with some training in point of care ultrasound (POCUS).

The primary objective of the study is to develop a model which can predict the change in ONSD after surgery based on various clinical and intraoperative parameters. We will model the difference in OND using a linear regression model with prespecified parameters, mainly-

1.Prolonged duration

2.Trendelenberg position (head down)

3.Pneumoperitonium (laparoscopy)

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-03
• Last Update Posted: 2021-02-26

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Abdominal surgery lasting for more than 4 hours.

Exclusion Criteria

Known retinal disease Known optic disease.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Perioperative variation of optic nerve sheath diameter	Measurement of optic nerve sheath diameter preoperatively and postoperatively before extubation/ in ICU in case if Patient is shifted intubated to icu

Secondary Outcome Measures

Name	Time	Method
Conjunctival edema associated? yes/ no	before and at the end of surgery

Trial Locations

Locations (1)

Tata Medical Center; 🇮🇳 Parganas, WEST BENGAL, India

Tata Medical Center

🇮🇳Parganas, WEST BENGAL, India

Arunangshu Chakraborty

Principal investigator

8910324933

dr.arunangshu@gmail.com