Comparative evaluation of half percent Ropivacaine with ropivacaine half percent and Dexmedetomidine in Ultrasound guided combined Femoral and Sciatic nerve block for lower limb surgeries. A Randomized clinical study
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the Anaesthetic and analgesic efficacy of the two drug combinations used in the study.
研究概览
简要总结
This study will be a randomized double blinded, prospective, comparative study, to be carried out in 60 patients, of ASA I and II undergoing lower limb surgery with combined femoral and sciatic nerve block.
The patients will be randomly divided into two groups of 30 each. Group A (n=30) will receive inj. 0.5% Ropivacaine (40ml) with 25 micrograms dexmedetomidine. Group B (n=30) will receive inj. 0.5% plain Ropivacaine (40ml).
The onset and duration of sensory block, motor block, post- operative analgesia, time to first rescue analgesic and side effects will be assessed and recorded.
All the findings and observations made during the entire study will be tabulated, graphically depicted whenever possible, statistically analysed and inference drawn to evaluate and compare the two groups on sensory and motor block onset, duration and side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Sex: Either sex Age: 18 to 65 years ASA Grade I or II patients scheduled for elective lower limb surgeries.
排除标准
- •1.Uncooperative patients / unwilling patients 2.Hypersensitivity to amide group of Local anaesthetic agents and dexmedetomidine 3.Patients having hypertension / diabetes mellitus / neuropathy / peripheral nerve injury 4.Pregnancy and lactation 5.Patient on anticoagulants or bleeding disorder 6.Local site infection.
结局指标
主要结局
To compare the Anaesthetic and analgesic efficacy of the two drug combinations used in the study.
时间窗: Outcome will be assessed during the intraoperative and postoperative period from the time of onset of sensory and motor blockade till the time of first rescue analgesia.
次要结局
未报告次要终点
研究者
Vigneshwaravibhava K
Regional Institute Of Medical Sciences, Manipur University