A prospective observational study: the effects of inhalational anesthetic and tracheal tube on airway resistance during general anesthesia
Not Applicable
Completed
- Conditions
- non
- Registration Number
- JPRN-UMIN000042544
- Lead Sponsor
- Tohoku University School of Medicine Anesthesiology and Perioperative Medicine
- Brief Summary
In the clinical study, the change in tidal volume per body weight, accompanied by gas composition change (2% sevoflurane in oxygen and with 0-30-60% of N2O), was recorded in 30 pediatric patients. The median tidal volume per body weight decreased by 10% when the respiratory gas density increased from 1.41 kg/m3 to 1.70 kg/m3, indicating a significant between-group difference (P < 0.0001).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients with respiratory diseases (2) Patients with difficulty in tracheal intubation (3) Patients whose surgical procedure affects ventilatory parameters (4) Patients with risk factors for malignant hyperthermia due to inhalation anesthetic
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in tidal volume due to changes in anesthetic gas composition or tracheal tube length
- Secondary Outcome Measures
Name Time Method ventilatory information (ventilator settings, airway pressure, flow velocity, resistance, anesthetic gas composition, tracheal tube length), biometric information (heart rate, blood pressure, oxygen saturation, end-tidal carbon dioxide tension)