The effect of vitamin D on severity of primary dysmenorrhea and amount of menstrual bleeding

Phase 2

• Conditions: primary dysmenorrhea.; primary dysmenorrhea

• Registration Number: IRCT201305212324N9
• Lead Sponsor: Vice chancellor for research, Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Healthy, iranian and single female students aged 18 to 25 years? With normal menstrual cycles (cycles lasted 21 to 35 days, mensturation lasting 3 to 7 days)? Experienced at least 4 consecutive painful periods in the past 6 months with the pain starting a few hours before or just after the onset of bleeding? No history of underlying disease cause of secondary dysmenorrhea sush as: endometriosis and adenomyosis,etc? Don’t do any regular exercise? Lack of stressful experiences within 3 months prior? Don’t use of oral contraceptives and hormonal drugs within 3 months prior? Taking no medications including calcium and vitamin D within 6 months prior? 25(OH)D serum level = 30 ng/ml and normal serum calcium? Having no unusual diets (vegetarian diets, special diet)? Don’t use of medicines that interact with vitamin D such as: hydantoin and barbiturates,etc? BMI = 30? No smoking and alcohol consumption.

Exclusion criteria: Lack of menstruation? Married during the study? Use of medications including calcium and vitamin D during the study? Use of oral contraceptives and hormonal drugs during the study ?Use of non-pharmacological methods of pain relief ?Intense psychological stress during the study? Start exercise during the study ?Don’t use of supplement or interventions intended ?Occurring gastrointestinal disorders after the consumption of supplement (Including vomiting 2 hours after the consumption of supplement ?(Unwillingness to continue research.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain score of primary dysmenorrhea. Timepoint: Before intervention, the first cycle after intervention, the Second cycle after intervention. Method of measurement: visual analog scale (VAS).;Amount of menstrual bleeding. Timepoint: Before intervention, the first cycle after intervention, the Second cycle after intervention. Method of measurement: Pictorial blood loss assessment chart.;Severity of primary dysmenorrhea. Timepoint: Before intervention, the first cycle after intervention, the Second cycle after intervention. Method of measurement: Verbal multidimensional scoring system (VMS).

Secondary Outcome Measures

Name	Time	Method
se of NSAIDs. Timepoint: Before intervention, the first cycle after intervention, the Second cycle after intervention. Method of measurement: Record sheet of NSAID use.