The effect of lumbar manipulation on neurometabolites of the thalamus in non-specific chronic low back pain patients

Not Applicable

Recruiting

• Conditions: nspecific Chronic Low Back Pain.; Dorsalgia, unspecified; M54.9

• Registration Number: IRCT20230103057029N1
• Lead Sponsor: Behbahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 7 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

16 patients with non-specific chronic back pain for more than three months, in the age range of 20 to 50 years
16 healthy people without any pain in the age range of 20 to 50 years.

Exclusion Criteria

Patients with chronic back pain with specific neurological origin and specific pathology (tumor, etc.), patients with neurological and rheumatoid disorders, diabetes, patients with broken ribs, vertebrae, and pelvis, tailbone syndrome, abdominal aortic aneurysm, neoplasm , neuropathy and radiculopathy, osteoporosis, fibromyalgia, pain in other areas of the body, injury and use of drug during the study.
People who used antidepressants and anxiety medications
Patients with non-specific chronic back pain who were treated for the last three months.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Thalamus Neurometabolits. Timepoint: Before and 5 weeks after the intervention. Method of measurement: Recording the neurometabolic map of the thalamus by magnetic resonance spectroscopy(MRS).

Secondary Outcome Measures

Name	Time	Method
Pain Intencity. Timepoint: Before and 5 weeks after the intervention. Method of measurement: Numerical Rating Scale.