Impact of 4 Sequential Measures on the Prevention of Ventilator Associated Pneumonia in Major Heart Surgery Intensive Care Unit

Maria Jesus Perez1 site in 1 country1,534 target enrollmentNovember 2009

ConditionsVentilator-associated Pneumonia

Overview

Phase: N/A
Intervention: Not specified
Conditions: Ventilator-associated Pneumonia
Sponsor: Maria Jesus Perez
Enrollment: 1534
Locations: 1
Primary Endpoint: Change (reduction) in the incidence density of Ventilator associated pneumonia (VAP)
Status: Completed
Last Updated: 12 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The objective of the investigators work was to evaluate the impact of 4 sequentially implemented measures for preventing VAP in a major heart surgery ICU. The measures were a specific training program, aspiration of subglottic secretions (ASS), introduction of an inclinometer to improve the semirecumbent position, and reinforcement of oral care with chlorhexidine.

Registry

clinicaltrials.gov

Start Date

November 2009

End Date

June 2012

Last Updated

12 years ago

Study Type

Interventional

Study Design

Single Group

Sex

All

Investigators

Sponsor

Maria Jesus Perez

Responsible Party

Sponsor Investigator

Principal Investigator

Maria Jesus Perez

Hospital General Universitario Gregorio Marañon

Eligibility Criteria

Inclusion Criteria

•all patients with heart surgery admitted in critical care unit during the study period

Exclusion Criteria

Not provided

Outcomes

Primary Outcomes

Change (reduction) in the incidence density of Ventilator associated pneumonia (VAP)

Time Frame: Baseline and up to 35 months

Change (reduction) in the incidence density of VAP

Secondary Outcomes

Change(length) in Intensive Care Unit (ICU) stay(Baseline and up to 35 months)
Change (number of days) in Mechanical Ventilator (MV) per ICU stay(Baseline and up to 35 months)
Change in mortality rate(Baseline and up to 35 months)
Change in cost of antimicrobial acquisition during ICU stay(Baseline and up to 35 months)
Change in compliance with the measures(Baseline and up to 35 months)