Comparison of post operative healing of extraction socket with and without calcium chloride activated platelet rich plasma-an invivo study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- The placement of calcium chloride activated platelet rich plasma gel in the extraction site will improve the healing property of tissue and faster wound healing
研究概览
简要总结
Platelet rich plasma (PRP) is a new approach to tissue regeneration and it is becomming a valuable adjunt to promote healing in many procedures in dental and oral surgery. PRP derives from the centrifugation of the patients own blood and it contains growth factors that influence wound healing.Placement of PRP in extraction socket improve wound healing and bone formation. PRP can be activated to form PRP gel thus cause degranulation of alpha granules present in platelets and releasing growth factors.Here I am using calcium chloride 10% solution for PRP activation to form gel and it is placed in extraction of case patients and evaluated for 3rd day 7th day and 14th day for clinical wound healing evaluation and 1st month and 3rd month for radiographic examination.
This prospective clinical trial is designed to compare bone filling and soft tissue healing with and without calcium chloride activated PRP in bilateral similar tooth extraction patients.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who needs bilateral similar tooth extraction Patients who will agreed for this study.
排除标准
- •Chain smoker Uncontrolled systemic illness Immunodeficiency pathology Patient with psychiatric problem Pregnant patient Platelet and hematological disorders Chemotherapy and radiotherapy patients Who needes surgical removal of tooth.
结局指标
主要结局
The placement of calcium chloride activated platelet rich plasma gel in the extraction site will improve the healing property of tissue and faster wound healing
时间窗: 14 days
次要结局
- This will help for bone formation in extraction socket, which will benefit for prosthetic rehabilitation.(3 months)