The Effect of Fermented Lingonberry Spray on Oral Health - The Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- The effects of fermented lingonberry spray in the mouth.
研究概览
简要总结
A human intervention study was performed to examine the antimicrobial effects of fermented lingonberry spray (FLJ spray) treatment, used for a period of 30 days.
详细描述
Traditional clinical oral examinations, periodontal status and sample gatherings were performed at start point, two and four weeks. Bleeding on probing (BOP), visible plaque index (VPI), probing pocket depths (PPD) were examined and active-matrix metalloproteinase - 8 (aMMP-8) mouthrinse assays (Cutt-off 20 ng/ml) were carried out. Additionally, stimulated and resting saliva, pH and buffering capacity were tested as saliva test. A questionnaire assessing dry mouth symptoms was also recorded from the patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy patients or patients with systemic diseases with good cognitive abilities
- •with or without xerostomia.
排除标准
- •use of other mouthwash products, including chlorhexidine
- •current use of antibiotics.
结局指标
主要结局
The effects of fermented lingonberry spray in the mouth.
时间窗: Up to one month
Changes of bleeding on probing (BOP), from six measurement point, visible plaque index (VPI), score 1-3, probing pocket depths (PPD) and active-matrix metalloproteinase - 8 (aMMP-8) mouthrinse assays (Cutt-off 20 ng/ml), numerical value were carried out to one month.
the time points on the levels of each salivary parameter were determined with the repeated measures ANOVA analysis.
时间窗: 6 weeks
次要结局
未报告次要终点