Change of OCT findings after Intravitreal Anti-VEGF injection in patients with diabetic tractional retinal detachment : A Randomized Controlled Trial
- Conditions
- Tractional retinal detachment in patient with proliferative diabetic retinopathyTractional retinal detachmentAnti VEGFdiabetic retinopathyOCT
- Registration Number
- TCTR20210524001
- Lead Sponsor
- Research Funds, Faculty of medicine, KK
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- All
- Target Recruitment
- 80
1. Age > 18 years
2. With the following characteristics
2.1) underlying disease of type 1 or type 2 diabetes mellitus
2.2) diagnosed with PDR with TRD requiring surgery
2.3) OCT scans on the enroll day with good interpretable quality showing fibrous traction on preretinal area and tractional retinal detachment
2.4) If two eyes are elligible, only one eye per patient (the eye with worse visual acuity) will be included in the study.
1. Patient with center-involved DME with macular edema from component other than traction
2. Patient with severe anterior segment pathology precluding OCT scans, fundus examination (i.e. dense cataract, dense vitreous hemorrhage)
3. Previous intraocular surgery (except uncomplicated cataract surgery)
4. Previous Injection into study eyes within 6 months
5. Patient contraindicated to intravitreal injection (i.e endophthalmitis)
6. Patient with other ocular pathology causing possible neovascularization, retinal detachment or fibrous traction in study eyes (Traumatic retinal detachment, Uveitis, Retinal vascular disease, Congenital vitreoretinopathy
7. Patient denied intravitreal injection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of tractional degree 1 month OCT
- Secondary Outcome Measures
Name Time Method Change of detachment degree 1 month OCT