Total Joint Replacement or Interpositional Arthroplasty for the Treatment of Arthritis in the Carpometacarpal Joint of the Thumb
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Osteoarthrosis of the Carpometacarpal Joint of the Thumb
- Sponsor
- Oslo University Hospital
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- quick-DASH
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
Interpositional arthroplasty is by many considered to be the current gold standard for the treatment of thumb carpometacarpal arthritis. The results are generally good, but the rehabilitation time can be long and failures are difficult to treat. Total joint replacements now exist with modern uncemented designs that can be an alternative treatment. Short term studies show that thumb function often is better and rehabilitation time shorter, however there is uncertainty with regards to the longevity of the implants. Currently no prospective randomized trials have compared these two treatment options. Our hypothesis is that the total joint replacement will give the same results or better when compared to the interpositional arthroplasty.
Detailed Description
Eligible: patients \>18 years with pain and dysfunction from the first cmc joint. Clinical and radiological arthritis. Exclusion: degenerative changes in the STT joint (all patients are assessed by CT), other injuries in the hand/thumb, pregnancy Outcome measures: quick-Dash, Nelson hospital score, range of motion, grip strength Complications are registered. The patients are observed for two years and the investigators aim to include a total of 40 patients.
Investigators
Rasmus Thorkildsen
Senior Consultant
Oslo University Hospital
Eligibility Criteria
Inclusion Criteria
- •CMC 1 arthritis
- •Pain and dysfunction
- •Adult patients
- •General good health
Exclusion Criteria
- •Pregnancy
- •STT arthritis (CT scan preoperatively for all patients)
- •Other injuries in thumb/hand
Outcomes
Primary Outcomes
quick-DASH
Time Frame: Baseline (preoperatively), and change from baseline postoperatively at 6 weeks, 3, 6, 12 and 24 months.
two-page questionnaire with VAS-scale for pain and function.
Secondary Outcomes
- Nelson hospital score(Baseline (preoperatively) and change from base line postoperatively at 6 weeks, 3, 6, 12 and 24 months.)